Search on: DNA TOPOISOMERASE IV 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   DNA Topoisomerase IV 
Descriptor Spanish:   Topoisomerasa de ADN IV 
Descriptor Portuguese:   DNA Topoisomerase IV 
Synonyms English:   Topo IV
Topoisomerase IV
Topoisomerase IV Subunit A
Topoisomerase IV Subunit B
parC Gene Product
parC Gene Product, Topo IV
parE Gene Product
parE Gene Product, Topo IV
Topoisomerase IV, DNA
parC Protein
parE Protein  
Tree Number:   D08.811.399.403.741.224
D12.776.097.256
Definition English:   A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication. 
History Note English:   2002; use DNA TOPOISOMERASE IV (NM) 1991-2001 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   36090 
Unique Identifier:   D027101 

Occurrence in VHL:
 

Similar:

 
DeCS CID-10 SciELO LILACS LIS